An application of ionic liquid for preparation of homogeneous collagen and alginate hydrogels for skin dressing

Ionic liquid due to its green nature as well as having the ability to dissolve biopolymer, was used in the preparation of collagen and alginate hydrogels. The collagen and alginate hydrogels were prepared in different ratios of collagen and alginate, labeled CA5040, CA6030 and CA7020. The prepared h...

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Main Authors: Iqbal, B., Muhammad, N., Jamal, A., Ahmad, P., Khan, Z.U.H., Rahim, A., Khan, A.S., Gonfa, G., Iqbal, J., Rehman, I.U.
Format: Article
Institution: Universiti Teknologi Petronas
Record Id / ISBN-0: utp-eprints.19349 /
Published: Elsevier B.V. 2017
Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028558505&doi=10.1016%2fj.molliq.2017.08.101&partnerID=40&md5=93e7f3e8593a3b2f94d64934f99c7a5c
http://eprints.utp.edu.my/19349/
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spelling utp-eprints.193492018-04-20T00:21:02Z An application of ionic liquid for preparation of homogeneous collagen and alginate hydrogels for skin dressing Iqbal, B. Muhammad, N. Jamal, A. Ahmad, P. Khan, Z.U.H. Rahim, A. Khan, A.S. Gonfa, G. Iqbal, J. Rehman, I.U. Ionic liquid due to its green nature as well as having the ability to dissolve biopolymer, was used in the preparation of collagen and alginate hydrogels. The collagen and alginate hydrogels were prepared in different ratios of collagen and alginate, labeled CA5040, CA6030 and CA7020. The prepared hydrogels were characterized with Fourier-transform infrared spectroscopy (FTIR), Scanning electron microscope (SEM), Thermogravimetric analysis (TGA) analysis. The samples were evaluated for water uptake behavior and mechanical properties using electrodynamic fatigue testing system. The biocompatibility was assessed through hemolysis and MTT assay on rat mesenchymal stem cells (rMSC) which showed satisfactory results. The drug loading and subsequent antibacterial properties were also performed. The prepared collagen and alginate hydrogels are suggested to be used for skin dressing. © 2017 Elsevier B.V. 2017 Article PeerReviewed https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028558505&doi=10.1016%2fj.molliq.2017.08.101&partnerID=40&md5=93e7f3e8593a3b2f94d64934f99c7a5c Iqbal, B. and Muhammad, N. and Jamal, A. and Ahmad, P. and Khan, Z.U.H. and Rahim, A. and Khan, A.S. and Gonfa, G. and Iqbal, J. and Rehman, I.U. (2017) An application of ionic liquid for preparation of homogeneous collagen and alginate hydrogels for skin dressing. Journal of Molecular Liquids, 243 . pp. 720-725. http://eprints.utp.edu.my/19349/
institution Universiti Teknologi Petronas
collection UTP Institutional Repository
description Ionic liquid due to its green nature as well as having the ability to dissolve biopolymer, was used in the preparation of collagen and alginate hydrogels. The collagen and alginate hydrogels were prepared in different ratios of collagen and alginate, labeled CA5040, CA6030 and CA7020. The prepared hydrogels were characterized with Fourier-transform infrared spectroscopy (FTIR), Scanning electron microscope (SEM), Thermogravimetric analysis (TGA) analysis. The samples were evaluated for water uptake behavior and mechanical properties using electrodynamic fatigue testing system. The biocompatibility was assessed through hemolysis and MTT assay on rat mesenchymal stem cells (rMSC) which showed satisfactory results. The drug loading and subsequent antibacterial properties were also performed. The prepared collagen and alginate hydrogels are suggested to be used for skin dressing. © 2017
format Article
author Iqbal, B.
Muhammad, N.
Jamal, A.
Ahmad, P.
Khan, Z.U.H.
Rahim, A.
Khan, A.S.
Gonfa, G.
Iqbal, J.
Rehman, I.U.
spellingShingle Iqbal, B.
Muhammad, N.
Jamal, A.
Ahmad, P.
Khan, Z.U.H.
Rahim, A.
Khan, A.S.
Gonfa, G.
Iqbal, J.
Rehman, I.U.
An application of ionic liquid for preparation of homogeneous collagen and alginate hydrogels for skin dressing
author_sort Iqbal, B.
title An application of ionic liquid for preparation of homogeneous collagen and alginate hydrogels for skin dressing
title_short An application of ionic liquid for preparation of homogeneous collagen and alginate hydrogels for skin dressing
title_full An application of ionic liquid for preparation of homogeneous collagen and alginate hydrogels for skin dressing
title_fullStr An application of ionic liquid for preparation of homogeneous collagen and alginate hydrogels for skin dressing
title_full_unstemmed An application of ionic liquid for preparation of homogeneous collagen and alginate hydrogels for skin dressing
title_sort application of ionic liquid for preparation of homogeneous collagen and alginate hydrogels for skin dressing
publisher Elsevier B.V.
publishDate 2017
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028558505&doi=10.1016%2fj.molliq.2017.08.101&partnerID=40&md5=93e7f3e8593a3b2f94d64934f99c7a5c
http://eprints.utp.edu.my/19349/
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score 11.62408

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