Numerical modelling and simulation of dielectrophoretic based WBC sorting using sidewall electrodes

With the advancement in microfluidic 'lab on a chip' systems, a mechanism to continuously separate submicron particles is needed. Dielectrophoresis (DEP) is a method that has demonstrated great potential in cell discrimination and isolation from mixture of many heterogeneous samples by uti...

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Main Authors: Yousuff, C.M., Hamid, N.H.B., Hussain, K.I., Ho, E.T.W.
Format: Article
Institution: Universiti Teknologi Petronas
Record Id / ISBN-0: utp-eprints.20178 /
Published: Institute of Electrical and Electronics Engineers Inc. 2017
Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011982195&doi=10.1109%2fICIAS.2016.7824090&partnerID=40&md5=8bb5c2e686c27e336c82e0772f75e3d1
http://eprints.utp.edu.my/20178/
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spelling utp-eprints.201782018-04-22T14:44:34Z Numerical modelling and simulation of dielectrophoretic based WBC sorting using sidewall electrodes Yousuff, C.M. Hamid, N.H.B. Hussain, K.I. Ho, E.T.W. With the advancement in microfluidic 'lab on a chip' systems, a mechanism to continuously separate submicron particles is needed. Dielectrophoresis (DEP) is a method that has demonstrated great potential in cell discrimination and isolation from mixture of many heterogeneous samples by utilizing the electrical properties of particles/cells and the medium. Here, we present a numerical model and simulation of microfluidic device with sidewall electrodes which generates non uniform field along the width of the micro channel to produce require negative DEP force which deflects the White Blood cells (WBC) from the sidewall to targeted outlet and red blood cells (RBCs) remain focused and followed the direction of the fluid flow and collected at waste outlet. We witnessed that, WBCs are separated with 100 efficiency from cell mixture at an applied voltage of 6 V with flow rate 0.2uL/min. © 2016 IEEE. Institute of Electrical and Electronics Engineers Inc. 2017 Article PeerReviewed https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011982195&doi=10.1109%2fICIAS.2016.7824090&partnerID=40&md5=8bb5c2e686c27e336c82e0772f75e3d1 Yousuff, C.M. and Hamid, N.H.B. and Hussain, K.I. and Ho, E.T.W. (2017) Numerical modelling and simulation of dielectrophoretic based WBC sorting using sidewall electrodes. International Conference on Intelligent and Advanced Systems, ICIAS 2016 . http://eprints.utp.edu.my/20178/
institution Universiti Teknologi Petronas
collection UTP Institutional Repository
description With the advancement in microfluidic 'lab on a chip' systems, a mechanism to continuously separate submicron particles is needed. Dielectrophoresis (DEP) is a method that has demonstrated great potential in cell discrimination and isolation from mixture of many heterogeneous samples by utilizing the electrical properties of particles/cells and the medium. Here, we present a numerical model and simulation of microfluidic device with sidewall electrodes which generates non uniform field along the width of the micro channel to produce require negative DEP force which deflects the White Blood cells (WBC) from the sidewall to targeted outlet and red blood cells (RBCs) remain focused and followed the direction of the fluid flow and collected at waste outlet. We witnessed that, WBCs are separated with 100 efficiency from cell mixture at an applied voltage of 6 V with flow rate 0.2uL/min. © 2016 IEEE.
format Article
author Yousuff, C.M.
Hamid, N.H.B.
Hussain, K.I.
Ho, E.T.W.
spellingShingle Yousuff, C.M.
Hamid, N.H.B.
Hussain, K.I.
Ho, E.T.W.
Numerical modelling and simulation of dielectrophoretic based WBC sorting using sidewall electrodes
author_sort Yousuff, C.M.
title Numerical modelling and simulation of dielectrophoretic based WBC sorting using sidewall electrodes
title_short Numerical modelling and simulation of dielectrophoretic based WBC sorting using sidewall electrodes
title_full Numerical modelling and simulation of dielectrophoretic based WBC sorting using sidewall electrodes
title_fullStr Numerical modelling and simulation of dielectrophoretic based WBC sorting using sidewall electrodes
title_full_unstemmed Numerical modelling and simulation of dielectrophoretic based WBC sorting using sidewall electrodes
title_sort numerical modelling and simulation of dielectrophoretic based wbc sorting using sidewall electrodes
publisher Institute of Electrical and Electronics Engineers Inc.
publishDate 2017
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011982195&doi=10.1109%2fICIAS.2016.7824090&partnerID=40&md5=8bb5c2e686c27e336c82e0772f75e3d1
http://eprints.utp.edu.my/20178/
_version_ 1741196330434297856
score 11.62408

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