Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model

Omega-3 poly unsaturated fatty acids (PUFA) particularly eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), have many health benefits including reducing the risk of cancer and cardiovascular disease. Recently, the use of ionic liquids (ILs) in lipid extraction from microalgae provides the...

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Main Authors: Motlagh, S.R., Harun, R., Biak, D.R.A., Hussain, S.A., Ghani, W.A.W.A.K., Khezri, R., Wilfred, C.D., Elgharbawy, A.A.M.
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Institution: Universiti Teknologi Petronas
Record Id / ISBN-0: utp-eprints.22141 /
Published: 2019
Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85061592115&doi=10.3390%2fmolecules24040713&partnerID=40&md5=f79c5ea397983deec9c019f05eead588
http://eprints.utp.edu.my/22141/
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spelling utp-eprints.221412019-02-28T06:01:13Z Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model Motlagh, S.R. Harun, R. Biak, D.R.A. Hussain, S.A. Ghani, W.A.W.A.K. Khezri, R. Wilfred, C.D. Elgharbawy, A.A.M. Omega-3 poly unsaturated fatty acids (PUFA) particularly eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), have many health benefits including reducing the risk of cancer and cardiovascular disease. Recently, the use of ionic liquids (ILs) in lipid extraction from microalgae provides the potential to overcome common drawbacks, offers several other benefits. To date, very limited researches are available to focus on extracting microalgae lipid and PUFA in particular by using ILs. The objective of current work is to screen the potential ILs that can be applied in EPA extraction. In this study, fast ILs screening was performed with the help of a conductor like screening model for real solvents (COSMO-RS) and the ILs with higher capacity values for use in extraction of EPA were compared. According to the results, the highest capacity for EPA extraction among 352 screened cation/anion combinations belongs to TMAmSO 4 . It is expected to achieve a higher yield of EPA once applying this combination as the solvent in the process of extraction. ILs with small anions were observed to have higher capacities, as well possessing higher charge density compared to larger ones, and therefore, they are more preferable for extraction purposes. Moreover, shorter alkyl chain cations are preferred when using imidazolium-based IL, which agrees with experimental data. © 2019 by the authors. 2019 Article NonPeerReviewed https://www.scopus.com/inward/record.uri?eid=2-s2.0-85061592115&doi=10.3390%2fmolecules24040713&partnerID=40&md5=f79c5ea397983deec9c019f05eead588 Motlagh, S.R. and Harun, R. and Biak, D.R.A. and Hussain, S.A. and Ghani, W.A.W.A.K. and Khezri, R. and Wilfred, C.D. and Elgharbawy, A.A.M. (2019) Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model. Molecules, 24 (4). http://eprints.utp.edu.my/22141/
institution Universiti Teknologi Petronas
collection UTP Institutional Repository
description Omega-3 poly unsaturated fatty acids (PUFA) particularly eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), have many health benefits including reducing the risk of cancer and cardiovascular disease. Recently, the use of ionic liquids (ILs) in lipid extraction from microalgae provides the potential to overcome common drawbacks, offers several other benefits. To date, very limited researches are available to focus on extracting microalgae lipid and PUFA in particular by using ILs. The objective of current work is to screen the potential ILs that can be applied in EPA extraction. In this study, fast ILs screening was performed with the help of a conductor like screening model for real solvents (COSMO-RS) and the ILs with higher capacity values for use in extraction of EPA were compared. According to the results, the highest capacity for EPA extraction among 352 screened cation/anion combinations belongs to TMAmSO 4 . It is expected to achieve a higher yield of EPA once applying this combination as the solvent in the process of extraction. ILs with small anions were observed to have higher capacities, as well possessing higher charge density compared to larger ones, and therefore, they are more preferable for extraction purposes. Moreover, shorter alkyl chain cations are preferred when using imidazolium-based IL, which agrees with experimental data. © 2019 by the authors.
format Article
author Motlagh, S.R.
Harun, R.
Biak, D.R.A.
Hussain, S.A.
Ghani, W.A.W.A.K.
Khezri, R.
Wilfred, C.D.
Elgharbawy, A.A.M.
spellingShingle Motlagh, S.R.
Harun, R.
Biak, D.R.A.
Hussain, S.A.
Ghani, W.A.W.A.K.
Khezri, R.
Wilfred, C.D.
Elgharbawy, A.A.M.
Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model
author_sort Motlagh, S.R.
title Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model
title_short Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model
title_full Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model
title_fullStr Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model
title_full_unstemmed Screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (EPA) from microalgae biomass using COSMO-RS model
title_sort screening of suitable ionic liquids as green solvents for extraction of eicosapentaenoic acid (epa) from microalgae biomass using cosmo-rs model
publishDate 2019
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85061592115&doi=10.3390%2fmolecules24040713&partnerID=40&md5=f79c5ea397983deec9c019f05eead588
http://eprints.utp.edu.my/22141/
_version_ 1741196574731534336
score 11.62408

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