Microbial biocompatibility of phosphonium- and ammonium-based ionic liquids

This present study is dedicated to the synthesis, characterization and microbial toxicity assessment of phosphonium- and ammonium-based ionic liquids (ILs) bearing four different anions phenylalalinate (Phe), taurinate (Tau), hydroxide (OH), and acetate (Ac). The structures of the subsequent ILs wer...

Full description

Main Authors: Sivapragasam, M., Jaganathan, J.R., Levêque, J.-M., Moniruzzaman, M., Abdul Mutalib, M.I.
Format: Article
Institution: Universiti Teknologi Petronas
Record Id / ISBN-0: utp-eprints.22244 /
Published: 2019
Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054598954&doi=10.1016%2fj.molliq.2018.10.022&partnerID=40&md5=19c4b4c5942a09f565f58f3bba77541c
http://eprints.utp.edu.my/22244/
Tags: Add Tag
No Tags, Be the first to tag this record!
id utp-eprints.22244
recordtype eprints
spelling utp-eprints.222442019-03-27T02:01:21Z Microbial biocompatibility of phosphonium- and ammonium-based ionic liquids Sivapragasam, M. Jaganathan, J.R. Levêque, J.-M. Moniruzzaman, M. Abdul Mutalib, M.I. This present study is dedicated to the synthesis, characterization and microbial toxicity assessment of phosphonium- and ammonium-based ionic liquids (ILs) bearing four different anions phenylalalinate (Phe), taurinate (Tau), hydroxide (OH), and acetate (Ac). The structures of the subsequent ILs were confirmed by 1H and 13C nuclear magnetic resonance (NMR). Physicochemical properties such as density, thermal stability, conductivity, surface tension, and refractive index were measured. Subsequently, the in vitro toxicity profiles of the ILs were determined for selected Gram-positive and Gram-negative bacteria in terms of inhibition zones (IZ), minimum inhibitory concentrations (MIC), and minimum bactericidal concentrations (MBC). The results showed that the ILs were in the range of �practically harmless� to �harmless�. The order of the same was OH > Ac > Tau > Phe, with phenylalalinate being the most toxic anion owing to its aromatic nature. With reference to the experimental results, the nature of the critical micellar concentrations and water octanol partitioning was discussed in the context of microbial toxicity. Hence, it was shown that anions, rather than cations, were the major contributors to toxicity. © 2018 Elsevier B.V. 2019 Article PeerReviewed https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054598954&doi=10.1016%2fj.molliq.2018.10.022&partnerID=40&md5=19c4b4c5942a09f565f58f3bba77541c Sivapragasam, M. and Jaganathan, J.R. and Levêque, J.-M. and Moniruzzaman, M. and Abdul Mutalib, M.I. (2019) Microbial biocompatibility of phosphonium- and ammonium-based ionic liquids. Journal of Molecular Liquids, 273 . pp. 107-115. http://eprints.utp.edu.my/22244/
institution Universiti Teknologi Petronas
collection UTP Institutional Repository
description This present study is dedicated to the synthesis, characterization and microbial toxicity assessment of phosphonium- and ammonium-based ionic liquids (ILs) bearing four different anions phenylalalinate (Phe), taurinate (Tau), hydroxide (OH), and acetate (Ac). The structures of the subsequent ILs were confirmed by 1H and 13C nuclear magnetic resonance (NMR). Physicochemical properties such as density, thermal stability, conductivity, surface tension, and refractive index were measured. Subsequently, the in vitro toxicity profiles of the ILs were determined for selected Gram-positive and Gram-negative bacteria in terms of inhibition zones (IZ), minimum inhibitory concentrations (MIC), and minimum bactericidal concentrations (MBC). The results showed that the ILs were in the range of �practically harmless� to �harmless�. The order of the same was OH > Ac > Tau > Phe, with phenylalalinate being the most toxic anion owing to its aromatic nature. With reference to the experimental results, the nature of the critical micellar concentrations and water octanol partitioning was discussed in the context of microbial toxicity. Hence, it was shown that anions, rather than cations, were the major contributors to toxicity. © 2018 Elsevier B.V.
format Article
author Sivapragasam, M.
Jaganathan, J.R.
Levêque, J.-M.
Moniruzzaman, M.
Abdul Mutalib, M.I.
spellingShingle Sivapragasam, M.
Jaganathan, J.R.
Levêque, J.-M.
Moniruzzaman, M.
Abdul Mutalib, M.I.
Microbial biocompatibility of phosphonium- and ammonium-based ionic liquids
author_sort Sivapragasam, M.
title Microbial biocompatibility of phosphonium- and ammonium-based ionic liquids
title_short Microbial biocompatibility of phosphonium- and ammonium-based ionic liquids
title_full Microbial biocompatibility of phosphonium- and ammonium-based ionic liquids
title_fullStr Microbial biocompatibility of phosphonium- and ammonium-based ionic liquids
title_full_unstemmed Microbial biocompatibility of phosphonium- and ammonium-based ionic liquids
title_sort microbial biocompatibility of phosphonium- and ammonium-based ionic liquids
publishDate 2019
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85054598954&doi=10.1016%2fj.molliq.2018.10.022&partnerID=40&md5=19c4b4c5942a09f565f58f3bba77541c
http://eprints.utp.edu.my/22244/
_version_ 1741196590863876096
score 11.62408

Similar Items