Zinc oxide and gold textured Janus nanowire integration in an impedimetric sensor for leptospirosis DNA-biomarker recognition

A �Janus particle� refers to the production of two materials in a single system and shows a difference in physical characteristics, and two surfaces participate in the formation with different chemistries. This research generated the Janus using a hybrid of zinc oxide (ZnO) and gold (Au) on the...

Full description

Main Authors: Haarindraprasad, R., Gopinath, S.C.B., Veeradassan, P.
Format: Article
Institution: Universiti Teknologi Petronas
Record Id / ISBN-0: utp-eprints.28991 /
Published: John Wiley and Sons Inc 2022
Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123498274&doi=10.1002%2fbab.2316&partnerID=40&md5=83dca626e34bb2f04a8e682a74876331
http://eprints.utp.edu.my/28991/
Tags: Add Tag
No Tags, Be the first to tag this record!
id utp-eprints.28991
recordtype eprints
spelling utp-eprints.289912022-03-17T02:56:58Z Zinc oxide and gold textured Janus nanowire integration in an impedimetric sensor for leptospirosis DNA-biomarker recognition Haarindraprasad, R. Gopinath, S.C.B. Veeradassan, P. A �Janus particle� refers to the production of two materials in a single system and shows a difference in physical characteristics, and two surfaces participate in the formation with different chemistries. This research generated the Janus using a hybrid of zinc oxide (ZnO) and gold (Au) on the sensor surface toward making high-performance DNA sensors. The Janus ZnO/Au-textured film was synthesized via the one-step sol�gel method, which involves a suitable ratio of a mixture of ZnO sol seed solution. The synthesized Janus ZnO/Au-textured film undergoes a low-temperature aqueous hydrothermal route to synthesize quasi-one-dimensional nanowires. The average grain size in the Janus ZnO/Au nanotextured wire was 41.60 nm. The fabricated nanotextured wire was further optimized by tuning the thickness and characterized by XRD and high-resolution microscopy. Electrical characterization was conducted on the Janus ZnO/Au nanotextured wire coupled with an interdigitated electrode sensor to detect the specific leptospirosis DNA strand. The generated device is capable of detecting lower DNA concentration at 1 � 10�13 M with a sensitivity of 8.54 MΩ M�1 cm�2. The high performance is attained on linear concentrations of 10�6�10�13 M with the determination coefficient, �I = 135437.63C�3609.07� R2 = 0.9551. A potential strategy is proposed as a base for developing different high-performance sensors. © 2022 International Union of Biochemistry and Molecular Biology, Inc. John Wiley and Sons Inc 2022 Article NonPeerReviewed https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123498274&doi=10.1002%2fbab.2316&partnerID=40&md5=83dca626e34bb2f04a8e682a74876331 Haarindraprasad, R. and Gopinath, S.C.B. and Veeradassan, P. (2022) Zinc oxide and gold textured Janus nanowire integration in an impedimetric sensor for leptospirosis DNA-biomarker recognition. Biotechnology and Applied Biochemistry . http://eprints.utp.edu.my/28991/
institution Universiti Teknologi Petronas
collection UTP Institutional Repository
description A �Janus particle� refers to the production of two materials in a single system and shows a difference in physical characteristics, and two surfaces participate in the formation with different chemistries. This research generated the Janus using a hybrid of zinc oxide (ZnO) and gold (Au) on the sensor surface toward making high-performance DNA sensors. The Janus ZnO/Au-textured film was synthesized via the one-step sol�gel method, which involves a suitable ratio of a mixture of ZnO sol seed solution. The synthesized Janus ZnO/Au-textured film undergoes a low-temperature aqueous hydrothermal route to synthesize quasi-one-dimensional nanowires. The average grain size in the Janus ZnO/Au nanotextured wire was 41.60 nm. The fabricated nanotextured wire was further optimized by tuning the thickness and characterized by XRD and high-resolution microscopy. Electrical characterization was conducted on the Janus ZnO/Au nanotextured wire coupled with an interdigitated electrode sensor to detect the specific leptospirosis DNA strand. The generated device is capable of detecting lower DNA concentration at 1 � 10�13 M with a sensitivity of 8.54 MΩ M�1 cm�2. The high performance is attained on linear concentrations of 10�6�10�13 M with the determination coefficient, �I = 135437.63C�3609.07� R2 = 0.9551. A potential strategy is proposed as a base for developing different high-performance sensors. © 2022 International Union of Biochemistry and Molecular Biology, Inc.
format Article
author Haarindraprasad, R.
Gopinath, S.C.B.
Veeradassan, P.
spellingShingle Haarindraprasad, R.
Gopinath, S.C.B.
Veeradassan, P.
Zinc oxide and gold textured Janus nanowire integration in an impedimetric sensor for leptospirosis DNA-biomarker recognition
author_sort Haarindraprasad, R.
title Zinc oxide and gold textured Janus nanowire integration in an impedimetric sensor for leptospirosis DNA-biomarker recognition
title_short Zinc oxide and gold textured Janus nanowire integration in an impedimetric sensor for leptospirosis DNA-biomarker recognition
title_full Zinc oxide and gold textured Janus nanowire integration in an impedimetric sensor for leptospirosis DNA-biomarker recognition
title_fullStr Zinc oxide and gold textured Janus nanowire integration in an impedimetric sensor for leptospirosis DNA-biomarker recognition
title_full_unstemmed Zinc oxide and gold textured Janus nanowire integration in an impedimetric sensor for leptospirosis DNA-biomarker recognition
title_sort zinc oxide and gold textured janus nanowire integration in an impedimetric sensor for leptospirosis dna-biomarker recognition
publisher John Wiley and Sons Inc
publishDate 2022
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123498274&doi=10.1002%2fbab.2316&partnerID=40&md5=83dca626e34bb2f04a8e682a74876331
http://eprints.utp.edu.my/28991/
_version_ 1741197180093333504
score 11.62408

Similar Items