Thermodynamic properties of flufenamic ionic liquids
Active pharmaceutical ingredients-ionic liquids (APIs-ILs) in which, when compared to active pharmaceutical ingredients hydrochloride (APIs-HCl), exhibits better solubility, increased thermal stability and significant enhancement in the efficiency of APIs. Three novel flufenamic-ILs were synthesized...
| Main Authors: | Romeli, F.J., Wilfred, C.D., Suhaila Shuib, A. |
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| Format: | Article |
| Institution: | Universiti Teknologi Petronas |
| Record Id / ISBN-0: | utp-eprints.31952 / |
| Published: |
Trans Tech Publications Ltd
2014
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| Online Access: |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84914133403&doi=10.4028%2fwww.scientific.net%2fAMM.625.586&partnerID=40&md5=c08b621cb0ffcaceafaa9f2240ba6850 http://eprints.utp.edu.my/31952/ |
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| Summary: |
Active pharmaceutical ingredients-ionic liquids (APIs-ILs) in which, when compared to active pharmaceutical ingredients hydrochloride (APIs-HCl), exhibits better solubility, increased thermal stability and significant enhancement in the efficiency of APIs. Three novel flufenamic-ILs were synthesized and their density and viscosities were determined and reported as a function of temperature. From the experimental density data the crystal energy, molecular volume and standard entropy was estimated. The result showed that the density and viscosities decrease with increasing temperature in these four ionic liquids. © 2014 Trans Tech Publications, Switzerland. |
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