STATISTICAL CHARACTERISTICS OF OCULAR BLOOD FLOW UNDER CAROTID ARTERY STENOSIS REFLECT VESSEL IMPAIRMENT AS STROKE BIOMARKER

Atherosclerosis, the major underlying cause of stroke, asymptomatically reduces blood flow to the brain and the eye, resulting in ocular impairment. However, real-time investigation of ocular blood flow (OBF) impairment under common carotid artery (CCA) stenosis is vague. This thesis aims to assess...

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Main Author: ISMAIL, AISHAH
Format: Thesis
Language: English
Institution: Universiti Teknologi Petronas
Record Id / ISBN-0: utp-utpedia.20729 /
Published: 2020
Subjects:
Q Science (General)
Online Access: http://utpedia.utp.edu.my/20729/1/Aishah%20Ismail_G03548.pdf
http://utpedia.utp.edu.my/20729/
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spelling utp-utpedia.207292021-09-08T16:04:05Z http://utpedia.utp.edu.my/20729/ STATISTICAL CHARACTERISTICS OF OCULAR BLOOD FLOW UNDER CAROTID ARTERY STENOSIS REFLECT VESSEL IMPAIRMENT AS STROKE BIOMARKER ISMAIL, AISHAH Q Science (General) Atherosclerosis, the major underlying cause of stroke, asymptomatically reduces blood flow to the brain and the eye, resulting in ocular impairment. However, real-time investigation of ocular blood flow (OBF) impairment under common carotid artery (CCA) stenosis is vague. This thesis aims to assess the impact of CCA stenosis on OBF longitudinally using a rabbit model. The OBF impairment was characterized to provide information about the impaired vessel condition. With these, the OBF characteristics were further classified to identify the potential biomarkers indicating impaired vessel conditions, hence providing information that indicates the risk of stroke onset. About 75% stenosis was created by tying the CCA with a plastic mandrel using a 9-0 nylon suture. 2020-12 Thesis NonPeerReviewed application/pdf en http://utpedia.utp.edu.my/20729/1/Aishah%20Ismail_G03548.pdf ISMAIL, AISHAH (2020) STATISTICAL CHARACTERISTICS OF OCULAR BLOOD FLOW UNDER CAROTID ARTERY STENOSIS REFLECT VESSEL IMPAIRMENT AS STROKE BIOMARKER. PhD thesis, Universiti Teknologi PETRONAS.
institution Universiti Teknologi Petronas
collection UTPedia
language English
topic Q Science (General)
spellingShingle Q Science (General)
ISMAIL, AISHAH
STATISTICAL CHARACTERISTICS OF OCULAR BLOOD FLOW UNDER CAROTID ARTERY STENOSIS REFLECT VESSEL IMPAIRMENT AS STROKE BIOMARKER
description Atherosclerosis, the major underlying cause of stroke, asymptomatically reduces blood flow to the brain and the eye, resulting in ocular impairment. However, real-time investigation of ocular blood flow (OBF) impairment under common carotid artery (CCA) stenosis is vague. This thesis aims to assess the impact of CCA stenosis on OBF longitudinally using a rabbit model. The OBF impairment was characterized to provide information about the impaired vessel condition. With these, the OBF characteristics were further classified to identify the potential biomarkers indicating impaired vessel conditions, hence providing information that indicates the risk of stroke onset. About 75% stenosis was created by tying the CCA with a plastic mandrel using a 9-0 nylon suture.
format Thesis
author ISMAIL, AISHAH
author_sort ISMAIL, AISHAH
title STATISTICAL CHARACTERISTICS OF OCULAR BLOOD FLOW UNDER CAROTID ARTERY STENOSIS REFLECT VESSEL IMPAIRMENT AS STROKE BIOMARKER
title_short STATISTICAL CHARACTERISTICS OF OCULAR BLOOD FLOW UNDER CAROTID ARTERY STENOSIS REFLECT VESSEL IMPAIRMENT AS STROKE BIOMARKER
title_full STATISTICAL CHARACTERISTICS OF OCULAR BLOOD FLOW UNDER CAROTID ARTERY STENOSIS REFLECT VESSEL IMPAIRMENT AS STROKE BIOMARKER
title_fullStr STATISTICAL CHARACTERISTICS OF OCULAR BLOOD FLOW UNDER CAROTID ARTERY STENOSIS REFLECT VESSEL IMPAIRMENT AS STROKE BIOMARKER
title_full_unstemmed STATISTICAL CHARACTERISTICS OF OCULAR BLOOD FLOW UNDER CAROTID ARTERY STENOSIS REFLECT VESSEL IMPAIRMENT AS STROKE BIOMARKER
title_sort statistical characteristics of ocular blood flow under carotid artery stenosis reflect vessel impairment as stroke biomarker
publishDate 2020
url http://utpedia.utp.edu.my/20729/1/Aishah%20Ismail_G03548.pdf
http://utpedia.utp.edu.my/20729/
_version_ 1741195658485825536
score 11.62408

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