Characterization of Ocular Blood Flow Dysregulation Due to Carotid Artery Stenosis Using Laser Speckle Flowgraphy

Carotid stenosis is caused by a build-up of plague in carotid arteries which carry oxygenated supply of blood to the brain. The narrowing of carotid arteries could eventually lead to a blockage. As the eye provides a direct access to our circulation, the ocular images offer a promising window to...

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Main Author: Kulothungan, Gayathiri
Format: Final Year Project
Language: English
Institution: Universiti Teknologi Petronas
Record Id / ISBN-0: utp-utpedia.23068 /
Published: Universiti Teknologi PETRONAS 2021
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Online Access: http://utpedia.utp.edu.my/23068/1/Dissertation_Gayathiri_24634.pdf
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spelling utp-utpedia.230682022-03-11T04:31:46Z http://utpedia.utp.edu.my/23068/ Characterization of Ocular Blood Flow Dysregulation Due to Carotid Artery Stenosis Using Laser Speckle Flowgraphy Kulothungan, Gayathiri TK Electrical engineering. Electronics Nuclear engineering Carotid stenosis is caused by a build-up of plague in carotid arteries which carry oxygenated supply of blood to the brain. The narrowing of carotid arteries could eventually lead to a blockage. As the eye provides a direct access to our circulation, the ocular images offer a promising window to assess the severity of stenosis and thus predict the likelihood of a stroke attack. This study aims to analyse and compare longitudinal time difference in pulse waveform criterions of ocular blood flow (OBF) between right eye as well as left eye, under common carotid artery stenosis. Information regarding vessel condition impairment can be derived by characterizing OBF impairment. Laser speckle flowgraphy (LSFG) is used to examine the pulse wave parameters of OBF, such as resistive index (RI), acceleration time index (ATI), flow acceleration index (FAI), falling rate (FR), rising rate (RR), blowout score (BOS), blowout time (BOT), mean blur rate (MBR) and the difference in the value of MBR at maximum and minimum point (MBRmax – MBRmin, AC) within the region of optic nerve head (ONH) vessel, tissue and overall. Universiti Teknologi PETRONAS 2021-01 Final Year Project NonPeerReviewed application/pdf en http://utpedia.utp.edu.my/23068/1/Dissertation_Gayathiri_24634.pdf Kulothungan, Gayathiri (2021) Characterization of Ocular Blood Flow Dysregulation Due to Carotid Artery Stenosis Using Laser Speckle Flowgraphy. Universiti Teknologi PETRONAS. (Submitted)
institution Universiti Teknologi Petronas
collection UTPedia
language English
topic TK Electrical engineering. Electronics Nuclear engineering
spellingShingle TK Electrical engineering. Electronics Nuclear engineering
Kulothungan, Gayathiri
Characterization of Ocular Blood Flow Dysregulation Due to Carotid Artery Stenosis Using Laser Speckle Flowgraphy
description Carotid stenosis is caused by a build-up of plague in carotid arteries which carry oxygenated supply of blood to the brain. The narrowing of carotid arteries could eventually lead to a blockage. As the eye provides a direct access to our circulation, the ocular images offer a promising window to assess the severity of stenosis and thus predict the likelihood of a stroke attack. This study aims to analyse and compare longitudinal time difference in pulse waveform criterions of ocular blood flow (OBF) between right eye as well as left eye, under common carotid artery stenosis. Information regarding vessel condition impairment can be derived by characterizing OBF impairment. Laser speckle flowgraphy (LSFG) is used to examine the pulse wave parameters of OBF, such as resistive index (RI), acceleration time index (ATI), flow acceleration index (FAI), falling rate (FR), rising rate (RR), blowout score (BOS), blowout time (BOT), mean blur rate (MBR) and the difference in the value of MBR at maximum and minimum point (MBRmax – MBRmin, AC) within the region of optic nerve head (ONH) vessel, tissue and overall.
format Final Year Project
author Kulothungan, Gayathiri
author_sort Kulothungan, Gayathiri
title Characterization of Ocular Blood Flow Dysregulation Due to Carotid Artery Stenosis Using Laser Speckle Flowgraphy
title_short Characterization of Ocular Blood Flow Dysregulation Due to Carotid Artery Stenosis Using Laser Speckle Flowgraphy
title_full Characterization of Ocular Blood Flow Dysregulation Due to Carotid Artery Stenosis Using Laser Speckle Flowgraphy
title_fullStr Characterization of Ocular Blood Flow Dysregulation Due to Carotid Artery Stenosis Using Laser Speckle Flowgraphy
title_full_unstemmed Characterization of Ocular Blood Flow Dysregulation Due to Carotid Artery Stenosis Using Laser Speckle Flowgraphy
title_sort characterization of ocular blood flow dysregulation due to carotid artery stenosis using laser speckle flowgraphy
publisher Universiti Teknologi PETRONAS
publishDate 2021
url http://utpedia.utp.edu.my/23068/1/Dissertation_Gayathiri_24634.pdf
http://utpedia.utp.edu.my/23068/
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score 11.62408