DEVELOPMENT OF THE IONIC LIQUID MODIFIED CHITOSAN-TRIPOLYPHOSPHATE MICROPARTICLES FOR CONTROLLING INSULIN RELEASE

The unstable Chitosan-Tripolyphosphate (CS-TPP) nanoparticles/microparticles (NPs/MPs) results in burst release of Insulin in hydrochloric acid (HCl), while partial or poor solubility of material limits drug release in phosphate buffer saline (PBS).

Main Author: SAFDAR, RIZWAN
Format: Thesis
Language: English
Institution: Universiti Teknologi Petronas
Record Id / ISBN-0: utp-utpedia.23122 /
Published: 2021
Subjects:
Online Access: http://utpedia.utp.edu.my/23122/1/Rizwan%20Safdar_G03279.pdf
http://utpedia.utp.edu.my/23122/
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Summary: The unstable Chitosan-Tripolyphosphate (CS-TPP) nanoparticles/microparticles (NPs/MPs) results in burst release of Insulin in hydrochloric acid (HCl), while partial or poor solubility of material limits drug release in phosphate buffer saline (PBS).