Valuation system connectivity is correlated with poly-drug use in young adults
Poly-drug consumption contributes to fatal overdose in more than half of all poly-drug users. Analyzing decision-making networks may give insight into the motivations behind poly-drug use. We correlated average functional connectivity of the valuation system (VS), executive control system (ECS) and...
| Main Authors: | Loganathan, K., Lv, J., Cropley, V., Zalesky, A., Ho, E.T.W. |
|---|---|
| Format: | Article |
| Institution: | Universiti Teknologi Petronas |
| Record Id / ISBN-0: | utp-eprints.29671 / |
| Published: |
Elsevier Ireland Ltd
2021
|
| Online Access: |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85109778725&doi=10.1016%2fj.neures.2021.06.006&partnerID=40&md5=e0fa4b716e6e89292c36f2cf2345b246 http://eprints.utp.edu.my/29671/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: |
Poly-drug consumption contributes to fatal overdose in more than half of all poly-drug users. Analyzing decision-making networks may give insight into the motivations behind poly-drug use. We correlated average functional connectivity of the valuation system (VS), executive control system (ECS) and valuation-control complex (VCC) in a large population sample (n = 992) with drug use behaviour. VS connectivity is correlated with sedative use, ECS connectivity is separately correlated with hallucinogens and opiates. Network connectivity is also correlated with drug use via two-way interactions with other substances including alcohol and tobacco. These preliminary findings can contribute to our understanding of the common combinations of substance co-use and associated neural patterns. © 2021 Elsevier B.V. and Japan Neuroscience Society |
|---|