Analytical method development and validation of anticancer agent, 5-fluorouracil, and its metabolites in biological matrices: An updated review

5-fluorouracil (5-FU) refers to a fluorinated pyrimidine analogue that has been widely used as an anticancer agent for colon, head, and neck cancers. Detection of 5-FU and its metabolites; 5-fluorouridine and 5-fluoro-2-deoxyuridine in biological samples allows optimization of pharmacotherapy and en...

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Main Authors: Semail, N.-F., Abdul Keyon, A.S., Saad, B., Noordin, S.S., Nik Mohamed Kamal, N.N.S., Mohamad Zain, N.N., Azizi, J., Kamaruzaman, S., Yahaya, N.
Format: Article
Institution: Universiti Teknologi Petronas
Record Id / ISBN-0: utp-eprints.29914 /
Published: Bellwether Publishing, Ltd. 2020
Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85087640894&doi=10.1080%2f10826076.2020.1781654&partnerID=40&md5=0411094d07b6b56c381025493618f166
http://eprints.utp.edu.my/29914/
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