Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation
We present a robot that enables high-content studies of alert adult Drosophila by combining operations including gentle picking; translations and rotations; characterizations of fly phenotypes and behaviors; microdissection; or release. To illustrate, we assessed fly morphology, tracked odor-evoked...
| Main Authors: | Savall, J., Ho, E.T.W., Huang, C., Maxey, J.R., Schnitzer, M.J. |
|---|---|
| Format: | Article |
| Institution: | Universiti Teknologi Petronas |
| Record Id / ISBN-0: | utp-eprints.31408 / |
| Published: |
Nature Publishing Group
2015
|
| Online Access: |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84934440605&doi=10.1038%2fnmeth.3410&partnerID=40&md5=463c4fa1ece7a8cb236600cc1265ce90 http://eprints.utp.edu.my/31408/ |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: |
We present a robot that enables high-content studies of alert adult Drosophila by combining operations including gentle picking; translations and rotations; characterizations of fly phenotypes and behaviors; microdissection; or release. To illustrate, we assessed fly morphology, tracked odor-evoked locomotion, sorted flies by sex, and dissected the cuticle to image neural activity. The robot's tireless capacity for precise manipulations enables a scalable platform for screening flies' complex attributes and behavioral patterns. © 2015 Nature America, Inc. All rights reserved. |
|---|