Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation

We present a robot that enables high-content studies of alert adult Drosophila by combining operations including gentle picking; translations and rotations; characterizations of fly phenotypes and behaviors; microdissection; or release. To illustrate, we assessed fly morphology, tracked odor-evoked...

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Main Authors: Savall, J., Ho, E.T.W., Huang, C., Maxey, J.R., Schnitzer, M.J.
Format: Article
Institution: Universiti Teknologi Petronas
Record Id / ISBN-0: utp-eprints.31408 /
Published: Nature Publishing Group 2015
Online Access: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84934440605&doi=10.1038%2fnmeth.3410&partnerID=40&md5=463c4fa1ece7a8cb236600cc1265ce90
http://eprints.utp.edu.my/31408/
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spelling utp-eprints.314082022-03-26T03:19:00Z Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation Savall, J. Ho, E.T.W. Huang, C. Maxey, J.R. Schnitzer, M.J. We present a robot that enables high-content studies of alert adult Drosophila by combining operations including gentle picking; translations and rotations; characterizations of fly phenotypes and behaviors; microdissection; or release. To illustrate, we assessed fly morphology, tracked odor-evoked locomotion, sorted flies by sex, and dissected the cuticle to image neural activity. The robot's tireless capacity for precise manipulations enables a scalable platform for screening flies' complex attributes and behavioral patterns. © 2015 Nature America, Inc. All rights reserved. Nature Publishing Group 2015 Article NonPeerReviewed https://www.scopus.com/inward/record.uri?eid=2-s2.0-84934440605&doi=10.1038%2fnmeth.3410&partnerID=40&md5=463c4fa1ece7a8cb236600cc1265ce90 Savall, J. and Ho, E.T.W. and Huang, C. and Maxey, J.R. and Schnitzer, M.J. (2015) Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation. Nature Methods, 12 (7). pp. 657-660. http://eprints.utp.edu.my/31408/
institution Universiti Teknologi Petronas
collection UTP Institutional Repository
description We present a robot that enables high-content studies of alert adult Drosophila by combining operations including gentle picking; translations and rotations; characterizations of fly phenotypes and behaviors; microdissection; or release. To illustrate, we assessed fly morphology, tracked odor-evoked locomotion, sorted flies by sex, and dissected the cuticle to image neural activity. The robot's tireless capacity for precise manipulations enables a scalable platform for screening flies' complex attributes and behavioral patterns. © 2015 Nature America, Inc. All rights reserved.
format Article
author Savall, J.
Ho, E.T.W.
Huang, C.
Maxey, J.R.
Schnitzer, M.J.
spellingShingle Savall, J.
Ho, E.T.W.
Huang, C.
Maxey, J.R.
Schnitzer, M.J.
Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation
author_sort Savall, J.
title Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation
title_short Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation
title_full Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation
title_fullStr Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation
title_full_unstemmed Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation
title_sort dexterous robotic manipulation of alert adult drosophila for high-content experimentation
publisher Nature Publishing Group
publishDate 2015
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-84934440605&doi=10.1038%2fnmeth.3410&partnerID=40&md5=463c4fa1ece7a8cb236600cc1265ce90
http://eprints.utp.edu.my/31408/
_version_ 1741197568593887232
score 11.62408

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